top of page
The Daily Leaflets


Feb 26, 20231 min read
What you don't know you know
You know what you know. Simple enough. What you don't know you don't know is always a challenge. In between- what you Know you don't know...


Feb 25, 20231 min read
Sine, Cosine, and DNA
Back in high school I had a graphing calculator (long before the age of smartphones… or even cell phones- OMG). It was a Texas...


Feb 24, 20232 min read
Surfing on the AI Hype cycle
I occasionally contemplate where we are on the hype cycle with regards to AI and Pharma. On one hand- the companies developing the tech...


Feb 23, 20232 min read
Insource your knowledge
The further along we go down the development line, the deeper the knowledge we accumulate on the product. This translates to lower risk...


Feb 22, 20231 min read
Time to clean up the Knowledge garage!
Start-ups in pharma are notoriously risky- risks are everywhere, literally. They start with a drug candidate which is 100% uncertain: It...


Feb 21, 20231 min read
Trees, Leaves, and Knowledge
When you map your knowledge, it quickly assumes the shape of a tree.


Oct 3, 20222 min read
We are time
We don't have time. We don't use time. We are time. As we walk through the arrow of time, we accumulate experience, knowledge,...


Sep 1, 20222 min read
Knowledge and Risk
Buddha said: "it is difficult to be thorough in learning and exhaustive in investigation". He was referring, of course, to the arduous...


Jul 7, 20222 min read
The top of the mountain...
We've been climbing the CMC Development mountain in the past few weeks, each session we picked a different track... We spent a great deal...


Jun 15, 20221 min read
The CMC Superhero
The CMC Team: ● Makes sure manufacturing operations are synchronized with clinical needs (be it for clinical trials or market) ● Manages...


May 31, 20222 min read
The CMC Train is full steam ahead!
The CMC Essentials Training course is running full steam ahead! Some key take-aways from the first 3 sessions: We discussed how the...


May 1, 20221 min read
To Ph.D or not to Ph.D
When I told my professor in Weizmann I decided not to pursue a Phd, he thought I lost my mind. “Why would you not want to be a...


Apr 4, 20221 min read
The CMC Triangle
The three cornerstones of CMC: Chemistry, Manufacturing and Controls, are interconnected and impact one another. In this talk, we draw...


Mar 13, 20221 min read
What is CMC?
If you have “CMC” in your job title, your family probably still thinks you’re a chemist of some sort… while that may be true, it neglects...


Feb 13, 20221 min read
A short journey into Pharmaceutical Development
The anticipation for the COVID vaccines brought Pharmaceutical Development to the spotlight as we all witnessed the entire process unfold...


Dec 29, 202111 min read
When risk meets your children
Should we vaccinate our children against COVID-19? What's the difference between deciding for yourself, and deciding for your child, when...


Dec 2, 20215 min read
Pharmaceutical Development, CMC and Beyond!
Would you take a pill for your headache if it made you extremely nauseous? Most likely not. Nevertheless, extreme nausea is a risk people...


Dec 2, 20213 min read
GMP Granola
GMP Granola is my private geeky joke that goes through my head every time I make Granola. In my early Granola making days, I had a...


Nov 1, 20211 min read
Reflection on CMC in the Biotech world
CMC, short for "Chemistry, Manufacturing, Controls", puts Chemistry in the spotlight, but it is our mastering of Biology that brought us...
bottom of page